Half of London Waterloo station will be closed for the whole of this weekend as South Western Railway carries out major track maintenance and renewal work on the lines.
Some lines between Waterloo and Clapham Junction will be closed, with a reduced service running in and out of the former.
A spokesman for the franchise said: “On Saturday approximately a third of the usual number of services will run from Waterloo, on Sunday approximately 50 per cent per cent of our usual number of services will run from Waterloo”.
On Sunday platforms 1-10 will be closed, a Network Rail spokesman confirmed.
South Western warned that most services will run to alternative timetables, with many train services in and out of Waterloo making additional stops or using alternative routes with longer journeys.
All lines in the Wimbledon area will also be closed, with replacement bus services will run on routes passing through this area.
South Western added that there will be no suburban services leaving London Waterloo this weekend however bus replacements will be in operation, services to Windsor and Reading will run but with amended timetables, services on our main line will run to a reduced service which will also be diverted via Chertsey resulting in longer journey times.”
There will be reduced service at Clapham Junction, with South Western services only calling at platforms three to six throughout the weekend.
Berrylands station will have no service, with customers asked to use local bus services instead.
Network Rail also said that there will be no services on the East Coast main line out of King’s Cross, further adding to the disruption.
No trains will be able to call at the station all weekend while the network operator continues with its £1.2bn programme of upgrades across the line.
Ed Akers, Principal Programme Sponsor for Network Rail, said: “We know that there have been numerous changes to services to and from London this year and we apologise for any inconvenience which this has caused.
“This work will now not impact on services until June and I would like to thank passengers for their continued patience whilst we work on the upgrade, which will bring huge benefits to passengers when completed.”
A spokesperson for train operators along the route urged passengers “to follow the travel advice issued and not to travel to or from London this weekend on these routes”.