Rightmove shares in £1bn crash as AI plans spook investors November 7, 2025 Shares in Rightmove nosedived on Friday morning after the property titan revealed a major-shakeup centred on upping AI spending. The group said it would invest £60m over the next three years, with a focus on leaning into new tech. The FTSE 100 firm slashed its short-term profitability targets amid the new plans. Company boss Johan [...]
Adair Turner: Crypto? It’s like buying tulips in 1635 November 7, 2025 As chair of the FSA at the height of the 2008 financial crisis, Adair Turner knows all about the anatomy of a global crash. Over 15 years on, exuberance in AI and opaque private credit markets have set warning systems flashing. Ali Lyon, spoke to the arch-technocrat to see whether the fears are justified, and [...]
Six Nations should stage Ireland matches in USA, but not England ones November 7, 2025 There have been calls this week for Six Nations matches to be played in the United States, and I agree. But it should never be England crossing the Atlantic, and should almost always be Ireland. Andy Farrell’s Ireland successfully staged an epic spectacle at Soldier Field in Chicago against New Zealand. The game was pretty [...]
Retail footfall sinks for sixth straight month as Brits fear Budget taxes November 7, 2025 Footfall at the UK’s shops has declined for the sixth consecutive month, marking another worrying sign for the retail sector. Total activity fell by 0.7 per cent in October, led by drops in shopping centre and retail park footfall, according to the British Retail Consortium (BRC). BRC chief Helen Dickinson said that nervousness around the [...]
Prothena Reports Third Quarter 2025 Financial Results and Business Highlights November 6, 2025 Net cash used in operating and investing activities was $40.6 million and $140.4 million for the third quarter and first nine months of 2025, respectively; quarter-end cash and restricted cash position was $331.7 million Roche to initiate the Phase 3 PARAISO clinical trial evaluating prasinezumab, a potential first-in-class anti-alpha-synuclein antibody, for early-stage Parkinson's disease by end of 2025 Novo Nordisk initiated the Phase 3 CLEOPATTRA clinical trial evaluating coramitug, a potential first-in-class amyloid depleter, for ATTR amyloidosis with cardiomyopathy Novo Nordisk to present Phase 2 results for coramitug during a late-breaking session at the American Heart Association Scientific Sessions on November 10, 2025 Bristol Myers Squibb obtained Fast Track designation from the U.S. FDA for BMS-986446 (PRX005), an anti-MTBR-tau-targeting antibody, for the treatment of Alzheimer’s disease Prothena will convene an Extraordinary General Meeting on November 19, 2025 to obtain shareholder approval on a proposal reducing share capital to create distributable reserves to support a share redemption program to be conducted in 2026 if deemed appropriate Potential to earn up to $105 million in aggregate clinical milestone payments by end of 2026 related to the advancement of coramitug for ATTR amyloidosis with cardiomyopathy by Novo Nordisk and PRX019 for neurodegenerative diseases by Bristol Myers Squibb
What does the Bank’s rate decision mean for your finances? November 6, 2025 UK households who were hoping for a rate cut today may be disappointed after the Bank of England held interest rates at four per cent. The decision came amid concerns surrounding high inflation ahead of Chancellor Rachel Reeves’ crunch Budget later this month. Governor Andrew Bailey, who had the deciding vote, said he would “prefer [...]
Tallest skyscraper outside London approved in £1bn project November 6, 2025 A £1bn project which will see the tallest UK skyscraper outside of London constructed in Greater Manchester has been approved. Developer Henley Investment Management has secured permission from Salford City Council for its scheme at Regent Retail Park in Ordsall Lane. The proposals include a 78-storey tower which, at 895ft (272m) tall, will be the [...]
From insights to impact, Leinster Rugby leverages data strategy to level up fan experience November 6, 2025 BearingPoint supports the club in creating a roadmap for personalized experiences and future-ready innovation.
Silence Therapeutics Reports Third Quarter 2025 Financial Results and Recent Business Highlights November 6, 2025 SANRECO Phase 2 study of divesiran in polycythemia vera (PV) fully enrolled; topline results anticipated in 3Q 2026 Strong balance sheet and cash runway into 2028
Rachel Reeves must resign if she hikes income tax November 6, 2025 Exactly a year ago today, which was exactly a week after Rachel Reeves’ first Budget – I wrote that the Chancellor’s policies would give Brits the hangover from hell. So, one year on, how are you feeling? My reference to a hangover was inspired by the government’s absurd post-Budget boast that they’d taken a penny [...]