BSE (formerly Bombay Stock Exchange) Selects ITRS to Strengthen Real-Time Monitoring and Operational Resilience February 23, 2026 Asia’s Oldest Stock Exchange Partners with ITRS to Strengthen Monitoring and Compliance
Ares Management Prices European Direct Lending CLO II at Over €300 Million February 23, 2026 Ares Management Corporation (NYSE: ARES) (“Ares”), a leading global alternative investment manager, announced today the pricing of its second European Direct Lending Collateralized Loan Obligation, Ares European Direct Lending CLO II (“EDL CLO II”), at over €300 million. Consistent with the underlying composition of its predecessor, EDL CLO II is a diversified CLO comprised entirely [...]
Prothena Reports Fourth Quarter and Full Year 2025 Financial Results, and Provides Financial Guidance and Business Highlights February 23, 2026 Net cash used in operating and investing activities was $23.3 million and $163.7 million for the fourth quarter and full year of 2025, respectively; quarter-end cash and restricted cash position was $308.4 million Prothena expects the full year 2026 net cash used in operating and investing activities to be $50 to $55 million and expects to end the year with approximately $255 million in cash (midpoint). Financial guidance does not include the potential to earn up to $105 million in aggregate clinical milestone payments from strategic partners in 2026 Roche initiated the Phase 3 PARAISO trial evaluating prasinezumab in early-stage Parkinson’s disease in 4Q 2025; primary completion expected in 2029 Novo Nordisk initiated the Phase 3 CLEOPATTRA trial evaluating coramitug in ATTR amyloidosis with cardiomyopathy in 4Q 2025; primary completion expected in 2029 Bristol Myers Squibb fully enrolled the Phase 2 TargetTau-1 trial evaluating BMS-986446 in early Alzheimer’s disease with primary completion expected in 1H 2027, completed a Phase 1 trial evaluating a subcutaneous formulation of BMS-986446 and obtained Fast Track designation from the U.S. FDA for BMS-986446 for the treatment of Alzheimer’s disease Prothena presented preclinical data on its TDP-43 CYTOPE® program at Neuroscience 2025 (SfN) and at the International Symposium on ALS/MND demonstrating the potential of Prothena’s CYTOPE® technology to target intracellular disease pathways At the Extraordinary General Meeting on November 19, 2025 Prothena obtained shareholder approval to reduce share capital to create distributable reserves to support a share redemption program to be conducted in 2026 if deemed appropriate Potential to earn up to $105 million in aggregate clinical milestone payments by end of 2026 related to the advancement of both coramitug for ATTR amyloidosis with cardiomyopathy by Novo Nordisk and PRX019 for neurodegenerative diseases by Bristol Myers Squibb
ActiveCampaign Backs Autonomous Marketing with Results Guarantee February 23, 2026 The company becomes first in category to guarantee marketing outcomes, signaling strong platform performance & commitment to customer success
BAE Systems Announces 2025 Full Year Results February 23, 2026 Charles Woodburn, Chief Executive, said: “Our results highlight another year of strong operational and financial performance, thanks to the outstanding dedication of our employees. In a new era of defence spending, driven by escalating security challenges, we’re well positioned to provide both the advanced conventional systems and disruptive technologies needed to protect the nations we [...]
AlgoSec Posts 37% YoY New Business Growth in 2025 as Enterprises Prioritise Application-Centric Security February 23, 2026 Over 90% gross dollar retention and 37% year-over-year new business growth reflect demand for visibility across complex hybrid environments
UK tech faces hiring crunch despite AI visa push February 23, 2026 Applications from overseas tech workers wanting to move to the UK have dropped significantly, adding to concerns over talent shortages in one of the economy’s faster growing sectors. New data by accountancy firm RSM UK found the number of international workers applying for a UK visa to work in tech dropped 11 per cent from [...]
FTSE 100 Live: Stocks jittery after Trump tariffs; Job vacancies fall February 23, 2026 Good morning and welcome back to the City AM liveblog. Tariffs are once more redefining market sentiment. Last Friday, a number of FTSE 100 stocks popped on the news President Donald Trump’s ‘Liberation Day’ levies had been struck down by the US Supreme Court. It marked a major boost to global markets after the top [...]
Job vacancies at lowest level since 2021 as London worst affected February 23, 2026 The UK’s job market took another hit after total vacancies fell to the lowest level since 2021, with London the region facing the biggest drop in open roles. The number of jobs advertised plummeted 16 per cent year-on-year to January, dipping below 700,000 for the first time since January 2021, according to job search platform [...]
Bank to business lending growth to halve amid global tensions February 23, 2026 UK bank to businesses lending growth is forecast to halve this year as firms feel the pinch of challenging conditions amid global tensions. Net growth in the value of lending from the banking sector to businesses is tipped to slow to 3.5 per cent this year, standing at nearly half of the 6.9 per cent [...]