Alkermes Announces Initiation of Phase 3 Brilliance Studies Evaluating Alixorexton for the Treatment of Narcolepsy Type 1 and Type 2 April 1, 2026 Alkermes plc (Nasdaq: ALKS) today announced the initiation of the Brilliance Studies, a phase 3 program evaluating the safety and efficacy of alixorexton compared to placebo in adults with narcolepsy type 1 (NT1) and narcolepsy type 2 (NT2). Alixorexton is the company’s novel, investigational, oral, selective orexin 2 receptor (OX2R) agonist in development for the [...]
Bank of England: UK economy risks ‘large and overlapping’ shocks April 1, 2026 The Bank of England has issued a major warning that the financial system is facing increasing risks of “large, frequent and potentially overlapping shocks” amid the volatility from the Middle East war‘ and ongoing market risks’s impact on energy and global markets. In the latest meeting of the central bank’s Financial Policy Committee top officials [...]
Oracle chops headcount as AI reshapes Big Tech workforce April 1, 2026 Oracle has begun a new round of global job cuts, as the software giant ramps up spending on AI infrastructure and follows a broader wave of layoffs across Big Tech. Employees across multiple divisions, including cloud, health, sales and Netsuite, were informed on Tuesday that their roles had been eliminated with immediate effect. In a [...]
Cavendish warns Iran conflict could damage long-term growth April 1, 2026 Heightened geopolitical tensions, including the Iran war, could damage investor confidence and suffocate long-term growth if they persist, UK investment bank Cavendish has warned. The AIM-listed group noted that while certain “macroeconomic conditions had been trending more positively”, including gradually declining interest rates and rising capital allocation into European markets, investor sentiment continued to be [...]
Two-thirds of hospitality firms to cut jobs as April tax rises ‘suffocate’ sector April 1, 2026 Two-thirds of hospitality businesses will be forced to cut jobs and one in seven will shut altogether as a direct result of “suffocating” April tax rises, leading trade bodies have found. More than half (51 per cent) of hospitality firms will cancel investment plans and 42 per cent will reduce trading hours, according to a [...]
Family-run construction firms pushed ‘to brink’ by inheritance tax April 1, 2026 Family-run construction firms are being pushed to the brink of insolvency by reforms to inheritance tax which undermine Labour’s housebuilding target, a trade body has warned. Plant-hire firms – which provide machinery and services to the construction sector – are almost always family run and are being forced to scale back by inheritance tax changes, [...]
Monzo and Revolut take banking battle to the playground April 1, 2026 Banks are turning their attention to the younger generation and in this week’s column Samuel Norman takes a look at the money to be made with Gen Alpha. The Tooth Fairy is losing her magic touch. After centuries of cultural dominance in the under-the-pillow money market, the primary dealer of calcium-for-cash faces a hostile takeover. [...]
D’YAVOL Single Estate Vodka Wins Gold Medal and “Best Bottle Design” at Australian International Vodka Awards 2025 March 31, 2026 D’YAVOL Single Estate Vodka has been honoured with a Gold Medal and the coveted title of ‘Best Bottle Design’ at the prestigious Australian International Vodka Awards 2025. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260330821521/en/ Crafted with precision and an unwavering commitment to quality, D’YAVOL Single Estate Vodka represents a seamless blend [...]
Awful April: brace for a wave of stealth tax rises March 31, 2026 April is upon us and the new tax year will usher in a range of tax hikes, despite the absence of any headline rate rises, with frozen thresholds, shrinking allowances and tighter reliefs set to hit families, workers and savers. The harsh impact will also be felt as Brits are hit with a wave of [...]
Fresha Becomes the Software Infrastructure of Choice for Multi-location Selfcare Businesses as Enterprise Growth Surges March 31, 2026 Fresha, the top-rated AI-powered booking platform for beauty and wellness, is witnessing significant enterprise growth as multi-location and large-team businesses increasingly choose Fresha to manage and scale their operations. Leading well-established brands, including Menspire, Ted’s Grooming Room, Gould Barbers, Masaj, Adams Barbers, The Art of Nails, and more, are among a growing cohort of enterprise [...]