Wolff, 30, is in her second year with the Oxfordshire-based team and hopes to become the first woman to race in F1 since Lella Lombardi in 1976.
However Moss, who scored 24 podium finishes in his 10-year career, said: “The mental stress would be pretty difficult for a lady to deal with in a practical fashion. I don’t think they have the aptitude to win a Formula One race.”
But Wolff hit back: “I completely disagree with him, it makes me cringe hearing that.
“I do believe that it’s possible, otherwise I wouldn’t be doing this.”