Manager Roberto Mancini made 11 changes to the side which beat Manchester United 6-1 on Sunday and the gamble looked like it had backfired when Nenad Milijas fired the home side into an early lead.
But three goals in three minutes shortly before half-time from Adam Johnson, Samir Nasri and Edin Dzeko turned the tide in City’s favour. Luca Scapuzzi and Dzeko again stretched the lead before Jamie O’Hara added a late consolation.
Elsewhere, a Luis Suarez brace, his first strike a goal of the season contender, helped Liverpool come from behind to win 2-1 at Stoke, who had taken a first-half lead through Kenwyne Jones.
Finally, Blackburn secured a much needed win for their under-fire manager Steve Kean. Newcastle scored twice in injury time to tie the match at 2-2 and force an extra 30 minutes. Rovers regained the lead through Morten Gamst Pedersen, only for Peter Lovenkrands to square the match from the spot. But with a shootout looming Gael Givet struck in the 120th minute to seal a 4-3 victory.
CARLING CUP | QUARTER FINALISTS
Arsenal, Manchester United Crystal Palace, Cardiff, Manchester City, Liverpool, Chelsea, Blackburn.
* Ties to be played on 29 / 30 November Arsenal, Manchester United Crystal Palace, Cardiff, Manchester City, Liverpool, Chelsea, Blackburn.
* Ties to be played on 29 / 30 November