The Welsh centre’s involvement in BBC television show Strictly Come Dancing has delayed his first appearance for the London club, with whom he signed a contract until the end of the season in October.
Saracens chief executive Ed Griffiths said: “If you’re looking at it, the Wembley match looks like a grand stage for what could be a grand occasion.
“Obviously, selection of the team is very much up to the coaches, but it’s funny how things seem to work out.
“Maybe Gavin Henson’s Saracens debut could take place on the grandest stage in English sport at Wembley Stadium.”
Henson has been out of the game for over a year, and his comeback could coincide with an extremely busy period in the domestic calendar, including the return of the Heineken Cup.
But Griffiths insisted Henson would be ready for action, saying: “He’s looking exceptional in training. The coaches are delighted with his progress. it won’t be long before we see him on the field for Saracens.”