Shares in pharmaceutical giant Shire fell in afternoon trading, despite it naming a new chief financial officer.
The company said Thomas Dittrich, currently chief financial officer of engineering and manufacturing company Sulzer, will begin a new role as its finance chief early next year.
Dittrich will join the company's board as an executive member, and become a member of the executive committee.
As well has his time at Sulzer, where he served as interim chief executive in 2015, Dittrich has spent time at Amgen, Dell and Booz & Co.
"Thomas is a talented global executive who will bring to Shire a broad range of experiences from both inside and outside the pharmaceutical industry," said Susan Kilsby, Shire's chairman.
"The board and I look forward to working with him during this transformational time in the company's history."
Shares in the company were down 2.5 per cent at 3,587.5p in mid-afternoon trading.