Eddie Jones has lamented the most injury-stricken England squad in his time as head coach ahead of next Saturday's first of three autumn internationals against Argentina.
Jonny May is the latest on the sick list and is expected to miss the visit of Argentina, while fellow wingers Jack Nowell and Elliot Daly have already been ruled out.
Joe Launchbury and Marcus Smith have suffered minor knocks during England's training camp while a number of high profile players including Kyle Sinckler, Manu Tuilagi and Billy Vunipola have long-term issues and were not selected.
"This is my third year in the job and I've found the players to be in the most difficult condition in this camp," said Jones.
"We've had the Lions guys come back, they've all had short pre-seasons. They're deconditioned.
"We've had four or five players come in with knocks from games which has stopped them from training and I had one or two either suffer an injury in training or post-training."
Jones said wing Marland Yarde, who was transferred from Harlequins to Sale Sharks after disciplinary issues this week, is still in his thinking.
"He is contention but we have to assess whether emotionally he'll be right to compete for an England spot," said Jones.
"He's left the club that he loved to join another. Is he in the right condition to compete for a spot? It's like having a relationship break up, sometimes it takes time for people to get over it and I'm not sure where he's at.
"We didn't not select him because of behaviour, it was because Denny [Solomona] scored more tries than him."