Tottenham will travel to Manchester United tomorrow without top scorer Harry Kane, who has been ruled out with a minor hamstring strain.
The England striker limped off towards the end of Spurs' 4-1 hammering of Liverpool last weekend, after scoring a brace that took him to the top of the Premier League scoring charts.
Spurs face United in a lunchtime kick-off between the two sides currently locked together on 20 points in third and second respectively.
"The doctor and medical staff made the decision to not take the risk," said Spurs boss Mauricio Pochettino.
"There is no sense in taking that risk and making the problem bigger."
Spurs confirmed the injury was a "minor strain to the left hamstring".
Travelling to Old Trafford, where Jose Mourinho's side have won their last five league games on the trot without conceding, without Kane will be a blow to Spurs who have lost their last three games at United without scoring.
Yet Pochettino will take cheer from last season's record of five wins and three draws without Kane in the side.
"Yes, you always want all the players available," said Pochettino. "It’s a problem. Play more or play less, we want them available to play.
"Like always, we believe in the collective, in the squad. During the season, sometimes some problems happen and you must trust all the players, all the squad."