White Stuff's chief executive Jeremy Seigal is leaving the business after four years at the helm.
Seigal joined the fashion and homeware retailer in 2013, having previously worked at AS Watson, owner of Superdrug, and The Perfume Shop.
During his time as chief executive, Seigal has overseen its expansion both online and on the high street, and its move into the German market.
In its most recent full-year results, White Stuff's earnings before interest, tax, depreciation and amortisation (Ebitda) fell 2.9 per cent.
Like-for-like sales grew 0.6 per cent, and total sales climbed 10 per cent to £144.6m.
Debbie Hewitt, chairman of White Stuff, said: "We are appreciative of the commitment and loyalty [Seigal] has shown throughout his time with us and he leaves with our very best wishes for the future as he embarks on the next chapter of his professional life."
Seigal will leave by the end of the year, and White Stuff is currently looking for a replacement.