Ocado is running the UK's first trial of autonomous grocery deliveries in Greenwich.
A self-driving "CargoPod" will deliver groceries around the homes in the Royal Arsenal Riverside development for 10 days, serving around one hundred customers.
The trial is part of the GATEway Project, which is attempting to bring automated transport to Greenwich.
Ocado Technology, which is an arm of the online supermarket and delivery company, said it was supporting the experiment to "be at the edge of what is possible". The retailer makes money through technology deals as well as through selling food, and has software agreements with other retailers such as Morrisons.
"We are always looking to come up with unique, innovative solutions to the real-world challenge of delivering groceries in densely-populated urban environments," said Ocado Technology's David Sharp.
Business minister Claire Perry said: "The UK has a rich history in the automotive sector, and through our modern industrial strategy the country is on the verge of leading the world in self-driving technology and the industrial opportunities it brings."
She said the project will bring the UK "another step closer" to having self-driving cars on the roads, which could ease traffic in cities and reduce emissions.