Debenhams and Spire Healthcare were the two biggest fallers on a buoyant FTSE 250 today following on from analysts' warnings.
Retailer Debenhams was down 4.45 per cent to 79.2p per share in early-afternoon trading, after a note from Goldman Sachs cast doubt on its profit outlook.
Analysts at Goldman Sachs said the outlook for profits for the retailer are modest by European standards, according to Reuters.
Meanwhile, Spire's share price was 6.96 per cent down at 306.1p per share after analysts at Investec downgraded the company's stock to a "sell" rating.
Spire's fall comes a month after it cut its revenue guidance for the full year, which the company blamed on a 39 per cent decline in revenues from NHS Local contracts over the four months to the end of October.
While Debenhams and Spire traded lower, the FTSE 250 was 0.48 per cent up at 17,637 points.